BDBM50201769 CHEMBL3416823

SMILES: [H][C@@]12CCN(C[C@@H]1c1cc(nc(n1)-c1ccncc1)C(CC)CC)[C@@H](CN)C2

InChI Key: InChIKey=DHSUFIFRCXENTO-OTWHNJEPSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50201769   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50201769 (CHEMBL3416823) Show SMILES [H][C@@]12CCN(C[C@@H]1c1cc(nc(n1)-c1ccncc1)C(CC)CC)[C@@H](CN)C2 |r| Show InChI InChI=1S/C22H31N5/c1-3-15(4-2)20-12-21(26-22(25-20)16-5-8-24-9-6-16)19-14-27-10-7-17(19)11-18(27)13-23/h5-6,8-9,12,15,17-19H,3-4,7,10-11,13-14,23H2,1-2H3/t17-,18+,19-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Stony Brook University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus ATCC 29213 N-terminal His6-tagged FtsZ GTPase activity expressed in Escherichia coli BL21(DE3) assessed as reduct...				Bioorg Med Chem 24: 6354-6369 (2016) Article DOI: 10.1016/j.bmc.2016.05.003 BindingDB Entry DOI: 10.7270/Q2SN0BZ0
					More data for this Ligand-Target Pair