BindingDB PrimarySearch

BDBM50202031 3-(4-((1-(4-cyclohexenylphenyl)-3-(3,5-dichlorophenyl)ureido)methyl)benzamido)propanoic acid::3-{4-[1-(4-Cyclohex-1-enylphenyl)-3-(3,5-dichlorophenyl)ureidomethyl]benzoylamino}propionicacid::CHEMBL386446

SMILES: OC(=O)CCNC(=O)c1ccc(CN(C(=O)Nc2cc(Cl)cc(Cl)c2)c2ccc(cc2)C2=CCCCC2)cc1

InChI Key: InChIKey=VHURVYZHODPCCB-UHFFFAOYSA-N

Data: 8 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50202031
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glucagon-like peptide 1 receptor (GLP-1) (Homo sapiens (Human))	BDBM50202031 (3-(4-((1-(4-cyclohexenylphenyl)-3-(3,5-dichlorophe...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of GLP1 receptor				J Med Chem 50: 113-28 (2007) Article DOI: 10.1021/jm058026u BindingDB Entry DOI: 10.7270/Q26M36GK
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Glucagon-like peptide 1 receptor (GLP-1) (Homo sapiens (Human))	BDBM50202031 (3-(4-((1-(4-cyclohexenylphenyl)-3-(3,5-dichlorophe...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity to human cloned GLP1R expressed in BHK cells				J Med Chem 51: 5387-96 (2008) Article DOI: 10.1021/jm7015599 BindingDB Entry DOI: 10.7270/Q2X34X9R
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Glucagon receptor (Rattus norvegicus)	BDBM50202031 (3-(4-((1-(4-cyclohexenylphenyl)-3-(3,5-dichlorophe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	122	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of rat glucagon receptor				J Med Chem 50: 113-28 (2007) Article DOI: 10.1021/jm058026u BindingDB Entry DOI: 10.7270/Q26M36GK
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Gastric inhibitory polypeptide receptor (Rattus norvegicus)	BDBM50202031 (3-(4-((1-(4-cyclohexenylphenyl)-3-(3,5-dichlorophe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	216	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity to GIPR in rat liver membrane				J Med Chem 51: 5387-96 (2008) Article DOI: 10.1021/jm7015599 BindingDB Entry DOI: 10.7270/Q2X34X9R
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50202031 (3-(4-((1-(4-cyclohexenylphenyl)-3-(3,5-dichlorophe...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity to human cloned GluR expressed in BHK cells				J Med Chem 51: 5387-96 (2008) Article DOI: 10.1021/jm7015599 BindingDB Entry DOI: 10.7270/Q2X34X9R
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Gastric inhibitory polypeptide receptor (Homo sapiens (Human))	BDBM50202031 (3-(4-((1-(4-cyclohexenylphenyl)-3-(3,5-dichlorophe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity to human cloned GIPR expressed in BHK cells				J Med Chem 51: 5387-96 (2008) Article DOI: 10.1021/jm7015599 BindingDB Entry DOI: 10.7270/Q2X34X9R
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Glucagon receptor (Rattus norvegicus)	BDBM50202031 (3-(4-((1-(4-cyclohexenylphenyl)-3-(3,5-dichlorophe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Binding affinity to GlucR in rat liver membrane				J Med Chem 51: 5387-96 (2008) Article DOI: 10.1021/jm7015599 BindingDB Entry DOI: 10.7270/Q2X34X9R
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Glucagon receptor (Homo sapiens (Human))	BDBM50202031 (3-(4-((1-(4-cyclohexenylphenyl)-3-(3,5-dichlorophe...) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Inhibition of human cloned glucagon receptor expressed in BHK cells				J Med Chem 50: 113-28 (2007) Article DOI: 10.1021/jm058026u BindingDB Entry DOI: 10.7270/Q26M36GK
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair