BDBM50202149 5-(3,5-bis(benzyloxy)benzylidene)-2-thioxothiazolidin-4-one::CHEMBL230514

SMILES: SC1=NC(=O)C(S1)=Cc1cc(OCc2ccccc2)cc(OCc2ccccc2)c1

InChI Key: InChIKey=XVYLEONEMYQIGD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202149   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) (Homo sapiens (Human))	BDBM50202149 (5-(3,5-bis(benzyloxy)benzylidene)-2-thioxothiazoli...) Show SMILES SC1=NC(=O)C(S1)=Cc1cc(OCc2ccccc2)cc(OCc2ccccc2)c1 |w:7.8,t:1| Show InChI InChI=1S/C24H19NO3S2/c26-23-22(30-24(29)25-23)13-19-11-20(27-15-17-7-3-1-4-8-17)14-21(12-19)28-16-18-9-5-2-6-10-18/h1-14H,15-16H2,(H,25,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of ADAMTS5				Bioorg Med Chem Lett 17: 1185-8 (2007) Article DOI: 10.1016/j.bmcl.2006.12.027 BindingDB Entry DOI: 10.7270/Q2PN95BB
					More data for this Ligand-Target Pair