BDBM50202153 5-(3-(4-methoxyphenoxy)benzylidene)-2-thioxothiazolidin-4-one::CHEMBL395985

SMILES: COc1ccc(Oc2cccc(C=C3SC(S)=NC3=O)c2)cc1

InChI Key: InChIKey=LJAOAHDPVQMLFB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202153   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) (Homo sapiens (Human))	BDBM50202153 (5-(3-(4-methoxyphenoxy)benzylidene)-2-thioxothiazo...) Show SMILES COc1ccc(Oc2cccc(C=C3SC(S)=NC3=O)c2)cc1 |w:12.11,c:16| Show InChI InChI=1S/C17H13NO3S2/c1-20-12-5-7-13(8-6-12)21-14-4-2-3-11(9-14)10-15-16(19)18-17(22)23-15/h2-10H,1H3,(H,18,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of ADAMTS5				Bioorg Med Chem Lett 17: 1185-8 (2007) Article DOI: 10.1016/j.bmcl.2006.12.027 BindingDB Entry DOI: 10.7270/Q2PN95BB
					More data for this Ligand-Target Pair