BDBM50202175 5-(3-(4-chlorophenoxy)benzylidene)-2-thioxothiazolidin-4-one::CHEMBL230619

SMILES: SC1=NC(=O)C(S1)=Cc1cccc(Oc2ccc(Cl)cc2)c1

InChI Key: InChIKey=IYDYEBIGANNFTO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202175   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) (Homo sapiens (Human))	BDBM50202175 (5-(3-(4-chlorophenoxy)benzylidene)-2-thioxothiazol...) Show SMILES SC1=NC(=O)C(S1)=Cc1cccc(Oc2ccc(Cl)cc2)c1 |w:7.8,t:1| Show InChI InChI=1S/C16H10ClNO2S2/c17-11-4-6-12(7-5-11)20-13-3-1-2-10(8-13)9-14-15(19)18-16(21)22-14/h1-9H,(H,18,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of ADAMTS5				Bioorg Med Chem Lett 17: 1185-8 (2007) Article DOI: 10.1016/j.bmcl.2006.12.027 BindingDB Entry DOI: 10.7270/Q2PN95BB
					More data for this Ligand-Target Pair