BDBM50202185 5-((5-(4-fluorophenethoxy)-1-phenyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methylene)-2-thioxothiazolidin-4-one::CHEMBL391928

SMILES: Fc1ccc(CCOc2c(C=C3SC(S)=NC3=O)c(nn2-c2ccccc2)C(F)(F)F)cc1

InChI Key: InChIKey=GJAAXQZMSBKVKM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202185   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5) (Homo sapiens (Human))	BDBM50202185 (5-((5-(4-fluorophenethoxy)-1-phenyl-3-(trifluorome...) Show SMILES Fc1ccc(CCOc2c(C=C3SC(S)=NC3=O)c(nn2-c2ccccc2)C(F)(F)F)cc1 |w:10.9,c:14| Show InChI InChI=1S/C22H15F4N3O2S2/c23-14-8-6-13(7-9-14)10-11-31-20-16(12-17-19(30)27-21(32)33-17)18(22(24,25)26)28-29(20)15-4-2-1-3-5-15/h1-9,12H,10-11H2,(H,27,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of ADAMTS5 by FRET assay				Bioorg Med Chem Lett 17: 1189-92 (2007) Article DOI: 10.1016/j.bmcl.2006.12.020 BindingDB Entry DOI: 10.7270/Q2JW8DK5
					More data for this Ligand-Target Pair