BDBM50202217 CHEMBL226131::bis(7-hydroxybenzo[b]furan-2-yl)methanone

SMILES: Oc1cccc2cc(oc12)C(=O)c1cc2cccc(O)c2o1

InChI Key: InChIKey=YJWAGWZPHAIDKY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202217   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50202217 (CHEMBL226131 | bis(7-hydroxybenzo[b]furan-2-yl)met...) Show SMILES Oc1cccc2cc(oc12)C(=O)c1cc2cccc(O)c2o1 Show InChI InChI=1S/C17H10O5/c18-11-5-1-3-9-7-13(21-16(9)11)15(20)14-8-10-4-2-6-12(19)17(10)22-14/h1-8,18-19H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of endogenous FLT3 autophosphorylation in EOL1 cells				Bioorg Med Chem 15: 2187-97 (2007) Article DOI: 10.1016/j.bmc.2006.12.011 BindingDB Entry DOI: 10.7270/Q2F47NT9
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Mus musculus (mouse))	BDBM50202217 (CHEMBL226131 | bis(7-hydroxybenzo[b]furan-2-yl)met...) Show SMILES Oc1cccc2cc(oc12)C(=O)c1cc2cccc(O)c2o1 Show InChI InChI=1S/C17H10O5/c18-11-5-1-3-9-7-13(21-16(9)11)15(20)14-8-10-4-2-6-12(19)17(10)22-14/h1-8,18-19H	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Regensburg Curated by ChEMBL					Assay Description Inhibition of endogenous PDGFRbeta autophosphorylation in Swiss 3T3 fibroblasts				Bioorg Med Chem 15: 2187-97 (2007) Article DOI: 10.1016/j.bmc.2006.12.011 BindingDB Entry DOI: 10.7270/Q2F47NT9
					More data for this Ligand-Target Pair