BDBM50202276 2-propenyl 2-[5-biphenylmethylidene-4-oxo-2-thioxothiazolidin-3-yl]-3-phenylpropanoate::CHEMBL396500

SMILES: [#6]=[#6]-[#6]-[#8]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-1-[#6](=S)-[#16]\[#6](=[#6](/c2ccccc2)-c2ccccc2)-[#6]-1=O

InChI Key: InChIKey=AMOBFOCXJTWNPG-QHCPKHFHSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202276   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
BCL-W (Homo sapiens (Human))	BDBM50202276 (2-propenyl 2-[5-biphenylmethylidene-4-oxo-2-thioxo...) Show SMILES [#6]=[#6]-[#6]-[#8]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-1-[#6](=S)-[#16]\[#6](=[#6](/c2ccccc2)-c2ccccc2)-[#6]-1=O Show InChI InChI=1S/C28H23NO3S2/c1-2-18-32-27(31)23(19-20-12-6-3-7-13-20)29-26(30)25(34-28(29)33)24(21-14-8-4-9-15-21)22-16-10-5-11-17-22/h2-17,23H,1,18-19H2/t23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assay				Bioorg Med Chem 15: 2167-76 (2007) Article DOI: 10.1016/j.bmc.2006.12.020 BindingDB Entry DOI: 10.7270/Q28W3F4C
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50202276 (2-propenyl 2-[5-biphenylmethylidene-4-oxo-2-thioxo...) Show SMILES [#6]=[#6]-[#6]-[#8]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-1-[#6](=S)-[#16]\[#6](=[#6](/c2ccccc2)-c2ccccc2)-[#6]-1=O Show InChI InChI=1S/C28H23NO3S2/c1-2-18-32-27(31)23(19-20-12-6-3-7-13-20)29-26(30)25(34-28(29)33)24(21-14-8-4-9-15-21)22-16-10-5-11-17-22/h2-17,23H,1,18-19H2/t23-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl2 protein by fluorescence polarization assay				Bioorg Med Chem 15: 2167-76 (2007) Article DOI: 10.1016/j.bmc.2006.12.020 BindingDB Entry DOI: 10.7270/Q28W3F4C
					More data for this Ligand-Target Pair