BDBM50202282 2-[5-(1-phenylethylidene)-4-oxo-2-thioxothiazolidin-3-yl]-4-methylpentanoic acid::CHEMBL242339

SMILES: CC(C)C[C@H](N1C(=S)S\C(=C(\C)c2ccccc2)C1=O)C(O)=O

InChI Key: InChIKey=SCEVCEGSVQEIQX-UROBUVALSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202282   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50202282 (2-[5-(1-phenylethylidene)-4-oxo-2-thioxothiazolidi...) Show SMILES CC(C)C[C@H](N1C(=S)S\C(=C(\C)c2ccccc2)C1=O)C(O)=O Show InChI InChI=1S/C17H19NO3S2/c1-10(2)9-13(16(20)21)18-15(19)14(23-17(18)22)11(3)12-7-5-4-6-8-12/h4-8,10,13H,9H2,1-3H3,(H,20,21)/b14-11-/t13-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.12E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl2 protein by fluorescence polarization assay				Bioorg Med Chem 15: 2167-76 (2007) Article DOI: 10.1016/j.bmc.2006.12.020 BindingDB Entry DOI: 10.7270/Q28W3F4C
					More data for this Ligand-Target Pair
BCL-W (Homo sapiens (Human))	BDBM50202282 (2-[5-(1-phenylethylidene)-4-oxo-2-thioxothiazolidi...) Show SMILES CC(C)C[C@H](N1C(=S)S\C(=C(\C)c2ccccc2)C1=O)C(O)=O Show InChI InChI=1S/C17H19NO3S2/c1-10(2)9-13(16(20)21)18-15(19)14(23-17(18)22)11(3)12-7-5-4-6-8-12/h4-8,10,13H,9H2,1-3H3,(H,20,21)/b14-11-/t13-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.83E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assay				Bioorg Med Chem 15: 2167-76 (2007) Article DOI: 10.1016/j.bmc.2006.12.020 BindingDB Entry DOI: 10.7270/Q28W3F4C
					More data for this Ligand-Target Pair