BDBM50202589 2-(4-chloro-phenyl)-3-[3-(7-chloroquinolin-4-ylamino)-propyl]-2,3-dihydrobenzo[e][1,3]thiazin-4-one::2-(4-chlorophenyl)-3-(3-(7-chloroquinolin-4-ylamino)propyl)-2H-benzo[e][1,3]thiazin-4(3H)-one::CHEMBL376236

SMILES: Clc1ccc(cc1)C1Sc2ccccc2C(=O)N1CCCNc1ccnc2cc(Cl)ccc12

InChI Key: InChIKey=YXQTUEZKBHGDPC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202589   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histidine-rich protein PFHRP-II (Plasmodium falciparum)	BDBM50202589 (2-(4-chloro-phenyl)-3-[3-(7-chloroquinolin-4-ylami...) Show SMILES Clc1ccc(cc1)C1Sc2ccccc2C(=O)N1CCCNc1ccnc2cc(Cl)ccc12 Show InChI InChI=1S/C26H21Cl2N3OS/c27-18-8-6-17(7-9-18)26-31(25(32)21-4-1-2-5-24(21)33-26)15-3-13-29-22-12-14-30-23-16-19(28)10-11-20(22)23/h1-2,4-12,14,16,26H,3,13,15H2,(H,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of beta-hematin polymerization				J Med Chem 50: 394-8 (2007) Article DOI: 10.1021/jm061002i BindingDB Entry DOI: 10.7270/Q24Q7W7N
					More data for this Ligand-Target Pair