BDBM50202595 3-[3-(7-chloroquinolin-4-ylamino)-propyl]-[1,3]thiazinan-4-one::CHEMBL219517

SMILES: Clc1ccc2c(NCCCN3CSCCC3=O)ccnc2c1

InChI Key: InChIKey=HMDVGPZCACDPND-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202595   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histidine-rich protein PFHRP-II (Plasmodium falciparum)	BDBM50202595 (3-[3-(7-chloroquinolin-4-ylamino)-propyl]-[1,3]thi...) Show SMILES Clc1ccc2c(NCCCN3CSCCC3=O)ccnc2c1 Show InChI InChI=1S/C16H18ClN3OS/c17-12-2-3-13-14(4-7-19-15(13)10-12)18-6-1-8-20-11-22-9-5-16(20)21/h2-4,7,10H,1,5-6,8-9,11H2,(H,18,19)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of beta-hematin polymerization				J Med Chem 50: 394-8 (2007) Article DOI: 10.1021/jm061002i BindingDB Entry DOI: 10.7270/Q24Q7W7N
					More data for this Ligand-Target Pair