BDBM50202612 3-[4-(7-chloroquinolin-4-ylamino)-butyl]-2,3-dihydro-benzo[e][1,3]thiazin-4-one::CHEMBL219109

SMILES: Clc1ccc2c(NCCCCN3CSc4ccccc4C3=O)ccnc2c1

InChI Key: InChIKey=IHLYMQFMMKFDIV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202612   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histidine-rich protein PFHRP-II (Plasmodium falciparum)	BDBM50202612 (3-[4-(7-chloroquinolin-4-ylamino)-butyl]-2,3-dihyd...) Show SMILES Clc1ccc2c(NCCCCN3CSc4ccccc4C3=O)ccnc2c1 Show InChI InChI=1S/C21H20ClN3OS/c22-15-7-8-16-18(9-11-24-19(16)13-15)23-10-3-4-12-25-14-27-20-6-2-1-5-17(20)21(25)26/h1-2,5-9,11,13H,3-4,10,12,14H2,(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
Central Drug Research Institute Curated by ChEMBL					Assay Description Inhibition of beta-hematin polymerization				J Med Chem 50: 394-8 (2007) Article DOI: 10.1021/jm061002i BindingDB Entry DOI: 10.7270/Q24Q7W7N
					More data for this Ligand-Target Pair