BDBM50202674 CHEMBL269352::N-(1-(3-acetamidobenzyl)piperidin-4-yl)-7-fluoro-4-oxo-4H-chromene-2-carboxamide

SMILES: CC(=O)Nc1cccc(CN2CCC(CC2)NC(=O)c2cc(=O)c3ccc(F)cc3o2)c1

InChI Key: InChIKey=QNCNYSGUYPUZKJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202674   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50202674 (CHEMBL269352 | N-(1-(3-acetamidobenzyl)piperidin-4...) Show SMILES CC(=O)Nc1cccc(CN2CCC(CC2)NC(=O)c2cc(=O)c3ccc(F)cc3o2)c1 Show InChI InChI=1S/C24H24FN3O4/c1-15(29)26-19-4-2-3-16(11-19)14-28-9-7-18(8-10-28)27-24(31)23-13-21(30)20-6-5-17(25)12-22(20)32-23/h2-6,11-13,18H,7-10,14H2,1H3,(H,26,29)(H,27,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of 125I-MCH from MCH-R1 expressed in IMR-32 cells				Bioorg Med Chem Lett 17: 874-8 (2007) Article DOI: 10.1016/j.bmcl.2006.11.065 BindingDB Entry DOI: 10.7270/Q2D50MMK
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50202674 (CHEMBL269352 | N-(1-(3-acetamidobenzyl)piperidin-4...) Show SMILES CC(=O)Nc1cccc(CN2CCC(CC2)NC(=O)c2cc(=O)c3ccc(F)cc3o2)c1 Show InChI InChI=1S/C24H24FN3O4/c1-15(29)26-19-4-2-3-16(11-19)14-28-9-7-18(8-10-28)27-24(31)23-13-21(30)20-6-5-17(25)12-22(20)32-23/h2-6,11-13,18H,7-10,14H2,1H3,(H,26,29)(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Displacement of 3H-dofetilide from hERG-expressing HEK membrane homogenates				Bioorg Med Chem Lett 17: 874-8 (2007) Article DOI: 10.1016/j.bmcl.2006.11.065 BindingDB Entry DOI: 10.7270/Q2D50MMK
					More data for this Ligand-Target Pair