BDBM50202759 CHEMBL231720::N-(4-(4-amino-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide

SMILES: COc1cc(ccc1NC(=O)c1cc2ccccc2n1C)-c1nn(C)c2ncnc(N)c12

InChI Key: InChIKey=HGLHTBMFKAIGGR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202759   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50202759 (CHEMBL231720 | N-(4-(4-amino-1-methyl-1H-pyrazolo[...) Show SMILES COc1cc(ccc1NC(=O)c1cc2ccccc2n1C)-c1nn(C)c2ncnc(N)c12 Show InChI InChI=1S/C23H21N7O2/c1-29-16-7-5-4-6-13(16)10-17(29)23(31)27-15-9-8-14(11-18(15)32-3)20-19-21(24)25-12-26-22(19)30(2)28-20/h4-12H,1-3H3,(H,27,31)(H2,24,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Bioresearch Center Curated by ChEMBL					Assay Description Inhibition of Lck				Bioorg Med Chem Lett 17: 1167-71 (2007) Article DOI: 10.1016/j.bmcl.2006.12.035 BindingDB Entry DOI: 10.7270/Q24Q7TN6
					More data for this Ligand-Target Pair