BDBM50202880 CHEMBL3914880

SMILES: [Br-].Cc1ccc(C[n+]2ccc3ccnc4-c5ccccc5-c2c34)cc1

InChI Key: InChIKey=PUOXKDOVAVIOSP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202880   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 1 (Homo sapiens (Human))	BDBM50202880 (CHEMBL3914880) Show SMILES [Br-].Cc1ccc(C[n+]2ccc3ccnc4-c5ccccc5-c2c34)cc1 Show InChI InChI=1S/C22H17N2/c1-15-6-8-16(9-7-15)14-24-13-11-17-10-12-23-21-18-4-2-3-5-19(18)22(24)20(17)21/h2-13H,14H2,1H3/q+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase 1 using pHOT1 as substrate after 30 mins by agarose gel electrophoresis				Bioorg Med Chem 24: 6119-6130 (2016) Article DOI: 10.1016/j.bmc.2016.02.028 BindingDB Entry DOI: 10.7270/Q2BG2QZJ
					More data for this Ligand-Target Pair