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SMILES: CN1CCN(CC1)C(CN1CCN(CCCCc2cccc3ccccc23)CC1)c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=IHHDHTXBALMXOF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202944   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50202944
PNG
((+/-)-1-methyl-4-{2-{4-[4-(1-naphthyl)butyl]pipera...)
Show SMILES CN1CCN(CC1)C(CN1CCN(CCCCc2cccc3ccccc23)CC1)c1ccc(cc1)C(F)(F)F |w:7.8|
Show InChI InChI=1S/C32H41F3N4/c1-36-17-23-39(24-18-36)31(28-12-14-29(15-13-28)32(33,34)35)25-38-21-19-37(20-22-38)16-5-4-8-27-10-6-9-26-7-2-3-11-30(26)27/h2-3,6-7,9-15,31H,4-5,8,16-25H2,1H3
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Similars
Article
PubMed
n/an/a 226n/an/an/an/an/an/a



Taisho Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Displacement of [125I]Nle4-D-Phe7-alpha-MSH from human MC4 receptor expressed in COS1 cells

Bioorg Med Chem 15: 1989-2005 (2007)


Article DOI: 10.1016/j.bmc.2006.12.039
BindingDB Entry DOI: 10.7270/Q2C53KHN
More data for this
Ligand-Target Pair