BDBM50203062 (S)-4-(4-(trifluoromethyl)phenethyl)-1-(6-((diethylamino)methyl)-1,2,3,4-tetrahydronaphthalen-2-yl)piperazin-2-one::CHEMBL389618

SMILES: CCN(CC)Cc1ccc2C[C@H](CCc2c1)N1CCN(CCc2ccc(cc2)C(F)(F)F)CC1=O

InChI Key: InChIKey=CHRVPWKDWJJZRT-SANMLTNESA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50203062   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50203062 ((S)-4-(4-(trifluoromethyl)phenethyl)-1-(6-((diethy...) Show SMILES CCN(CC)Cc1ccc2C[C@H](CCc2c1)N1CCN(CCc2ccc(cc2)C(F)(F)F)CC1=O Show InChI InChI=1S/C28H36F3N3O/c1-3-32(4-2)19-22-5-8-24-18-26(12-9-23(24)17-22)34-16-15-33(20-27(34)35)14-13-21-6-10-25(11-7-21)28(29,30)31/h5-8,10-11,17,26H,3-4,9,12-16,18-20H2,1-2H3/t26-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity at MCHR1 by flash plate radioligand binding assay				Bioorg Med Chem 15: 2092-105 (2007) Article DOI: 10.1016/j.bmc.2006.12.028 BindingDB Entry DOI: 10.7270/Q23R0SK8
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50203062 ((S)-4-(4-(trifluoromethyl)phenethyl)-1-(6-((diethy...) Show SMILES CCN(CC)Cc1ccc2C[C@H](CCc2c1)N1CCN(CCc2ccc(cc2)C(F)(F)F)CC1=O Show InChI InChI=1S/C28H36F3N3O/c1-3-32(4-2)19-22-5-8-24-18-26(12-9-23(24)17-22)34-16-15-33(20-27(34)35)14-13-21-6-10-25(11-7-21)28(29,30)31/h5-8,10-11,17,26H,3-4,9,12-16,18-20H2,1-2H3/t26-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Procter & Gamble Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of MCHR1				Bioorg Med Chem 15: 2092-105 (2007) Article DOI: 10.1016/j.bmc.2006.12.028 BindingDB Entry DOI: 10.7270/Q23R0SK8
					More data for this Ligand-Target Pair