BDBM50203107 4-((1,4-dimethyl-1H-indol-3-yl)methylene)-3-(4-methyl-1,2,3-thiadiazol-5-yl)-1H-pyrazol-5(4H)-one::CHEMBL250394

SMILES: Cc1cccc2n(C)cc(C=c3c(=O)[nH][nH]\c3=c3/snnc3=C)c12

InChI Key: InChIKey=AIIIXBKURHRFKB-SRCHDXGKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50203107 (4-((1,4-dimethyl-1H-indol-3-yl)methylene)-3-(4-met...) Show SMILES Cc1cccc2n(C)cc(C=c3c(=O)[nH][nH]\c3=c3/snnc3=C)c12 |w:10.9| Show InChI InChI=1S/C17H15N5OS/c1-9-5-4-6-13-14(9)11(8-22(13)3)7-12-15(19-20-17(12)23)16-10(2)18-21-24-16/h4-8,19H,2H2,1,3H3,(H,20,23)/b12-7?,16-15-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon Inc. Curated by ChEMBL					Assay Description Inhibition of human cytoplasmic VEGFR2 expressed in baculovirus after 15 mins by time resolved fluorescence assay				Bioorg Med Chem Lett 17: 1793-8 (2007) Article DOI: 10.1016/j.bmcl.2006.12.054 BindingDB Entry DOI: 10.7270/Q20001SB
					More data for this Ligand-Target Pair