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SMILES: Cc1ccc(CC(=O)N2CCC(CCNc3ncccn3)CC2)cc1

InChI Key: InChIKey=VSSRALNHWPBCRX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203307   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50203307
PNG
(4-methylbenzyl 4-[2-(pyrimidin-2-ylamino)ethyl]pip...)
Show SMILES Cc1ccc(CC(=O)N2CCC(CCNc3ncccn3)CC2)cc1
Show InChI InChI=1S/C20H26N4O/c1-16-3-5-18(6-4-16)15-19(25)24-13-8-17(9-14-24)7-12-23-20-21-10-2-11-22-20/h2-6,10-11,17H,7-9,12-15H2,1H3,(H,21,22,23)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

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PC cid
PC sid
UniChem
Article
PubMed
 3.18E+3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H](E)-N1-(2-methoxybenzyl)cinnamamidine from human NR2B expressed in Ltk- cells

J Med Chem 50: 807-19 (2007)


Article DOI: 10.1021/jm060983w
BindingDB Entry DOI: 10.7270/Q2FX7944
More data for this
Ligand-Target Pair