BDBM50203309 4-methylbenzyl 4-(pyrimidin-2-ylamino)piperidine-1-carboxylate::CHEMBL374658

SMILES: Cc1ccc(COC(=O)N2CCC(CC2)Nc2ncccn2)cc1

InChI Key: InChIKey=UCWDXVNBJQGZMP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203309   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50203309 (4-methylbenzyl 4-(pyrimidin-2-ylamino)piperidine-1...) Show SMILES Cc1ccc(COC(=O)N2CCC(CC2)Nc2ncccn2)cc1 Show InChI InChI=1S/C18H22N4O2/c1-14-3-5-15(6-4-14)13-24-18(23)22-11-7-16(8-12-22)21-17-19-9-2-10-20-17/h2-6,9-10,16H,7-8,11-13H2,1H3,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H](E)-N1-(2-methoxybenzyl)cinnamamidine from human NR2B expressed in Ltk- cells				J Med Chem 50: 807-19 (2007) Article DOI: 10.1021/jm060983w BindingDB Entry DOI: 10.7270/Q2FX7944
					More data for this Ligand-Target Pair