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SMILES: Cc1ccc(COC(=O)N2CCC(COc3ncccn3)CC2)cc1

InChI Key: InChIKey=PPFNSHXKLMCXLU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203316   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50203316
PNG
(4-methylbenzyl 4-[(pyrimidin-2-yloxy)methyl]piperi...)
Show SMILES Cc1ccc(COC(=O)N2CCC(COc3ncccn3)CC2)cc1
Show InChI InChI=1S/C19H23N3O3/c1-15-3-5-16(6-4-15)14-25-19(23)22-11-7-17(8-12-22)13-24-18-20-9-2-10-21-18/h2-6,9-10,17H,7-8,11-14H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

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PC cid
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UniChem
Article
PubMed
 7.40E+3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H](E)-N1-(2-methoxybenzyl)cinnamamidine from human NR2B expressed in Ltk- cells

J Med Chem 50: 807-19 (2007)


Article DOI: 10.1021/jm060983w
BindingDB Entry DOI: 10.7270/Q2FX7944
More data for this
Ligand-Target Pair