BDBM50203318 4-methylbenzyl 4-{[methyl(pyrimidin-2-yl)amino]methyl}-piperidine-1-carboxylate::CHEMBL218463

SMILES: CN(CC1CCN(CC1)C(=O)OCc1ccc(C)cc1)c1ncccn1

InChI Key: InChIKey=IQPLYVYZAILDSZ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203318   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50203318 (4-methylbenzyl 4-{[methyl(pyrimidin-2-yl)amino]met...) Show SMILES CN(CC1CCN(CC1)C(=O)OCc1ccc(C)cc1)c1ncccn1 Show InChI InChI=1S/C20H26N4O2/c1-16-4-6-18(7-5-16)15-26-20(25)24-12-8-17(9-13-24)14-23(2)19-21-10-3-11-22-19/h3-7,10-11,17H,8-9,12-15H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H](E)-N1-(2-methoxybenzyl)cinnamamidine from human NR2B expressed in Ltk- cells				J Med Chem 50: 807-19 (2007) Article DOI: 10.1021/jm060983w BindingDB Entry DOI: 10.7270/Q2FX7944
					More data for this Ligand-Target Pair