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SMILES: O=C(NCc1ccccc1)N1CCC(CNc2ncccn2)CC1

InChI Key: InChIKey=VTMJLFSAQVGRBC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203322   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 2B


(Homo sapiens (Human))		BDBM50203322
PNG
(CHEMBL218460 | N-benzyl-4-[(pyrimidin-2-ylamino)me...)
Show SMILES O=C(NCc1ccccc1)N1CCC(CNc2ncccn2)CC1
Show InChI InChI=1S/C18H23N5O/c24-18(22-14-15-5-2-1-3-6-15)23-11-7-16(8-12-23)13-21-17-19-9-4-10-20-17/h1-6,9-10,16H,7-8,11-14H2,(H,22,24)(H,19,20,21)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

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PC cid
PC sid
UniChem
Article
PubMed
 1.17E+3n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H](E)-N1-(2-methoxybenzyl)cinnamamidine from human NR2B expressed in Ltk- cells

J Med Chem 50: 807-19 (2007)


Article DOI: 10.1021/jm060983w
BindingDB Entry DOI: 10.7270/Q2FX7944
More data for this
Ligand-Target Pair