BDBM50203324 4-tert-butylbenzyl 4-[(2-pyrimidinylamino)methyl]-1-piperidinecarboxylate::CHEMBL217940

SMILES: CC(C)(C)c1ccc(COC(=O)N2CCC(CNc3ncccn3)CC2)cc1

InChI Key: InChIKey=QMKIWWSSEBBOLG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203324   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Homo sapiens (Human))	BDBM50203324 (4-tert-butylbenzyl 4-[(2-pyrimidinylamino)methyl]-...) Show SMILES CC(C)(C)c1ccc(COC(=O)N2CCC(CNc3ncccn3)CC2)cc1 Show InChI InChI=1S/C22H30N4O2/c1-22(2,3)19-7-5-18(6-8-19)16-28-21(27)26-13-9-17(10-14-26)15-25-20-23-11-4-12-24-20/h4-8,11-12,17H,9-10,13-16H2,1-3H3,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H](E)-N1-(2-methoxybenzyl)cinnamamidine from human NR2B expressed in Ltk- cells				J Med Chem 50: 807-19 (2007) Article DOI: 10.1021/jm060983w BindingDB Entry DOI: 10.7270/Q2FX7944
					More data for this Ligand-Target Pair