BDBM50203350 3-(3-chloro-4-fluorophenyl)-1-(6-cyano-1,2,3,4-tetrahydronaphthalen-2-yl)-1-(3-(4-methylpiperazin-1-yl)propyl)urea::CHEMBL216066

SMILES: CN1CCN(CCCN(C2CCc3cc(ccc3C2)C#N)C(=O)Nc2ccc(F)c(Cl)c2)CC1

InChI Key: InChIKey=GQQWSGJBHQVUSW-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50203350 (3-(3-chloro-4-fluorophenyl)-1-(6-cyano-1,2,3,4-tet...) Show SMILES CN1CCN(CCCN(C2CCc3cc(ccc3C2)C#N)C(=O)Nc2ccc(F)c(Cl)c2)CC1 Show InChI InChI=1S/C26H31ClFN5O/c1-31-11-13-32(14-12-31)9-2-10-33(26(34)30-22-6-8-25(28)24(27)17-22)23-7-5-20-15-19(18-29)3-4-21(20)16-23/h3-4,6,8,15,17,23H,2,5,7,9-14,16H2,1H3,(H,30,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Drug Discovery Inc. Curated by ChEMBL					Assay Description Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 1718-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.080 BindingDB Entry DOI: 10.7270/Q26H4H3Q
					More data for this Ligand-Target Pair