BDBM50203357 3-(3-chloro-4-fluorophenyl)-1-(7-methoxy-1,2,3,4-tetrahydronaphthalen-2-yl)-1-(3-(4-methylpiperazin-1-yl)propyl)urea::CHEMBL216286

SMILES: COc1ccc2CCC(Cc2c1)N(CCCN1CCN(C)CC1)C(=O)Nc1ccc(F)c(Cl)c1

InChI Key: InChIKey=GIMYUPJVFIIFIM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203357   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50203357 (3-(3-chloro-4-fluorophenyl)-1-(7-methoxy-1,2,3,4-t...) Show SMILES COc1ccc2CCC(Cc2c1)N(CCCN1CCN(C)CC1)C(=O)Nc1ccc(F)c(Cl)c1 Show InChI InChI=1S/C26H34ClFN4O2/c1-30-12-14-31(15-13-30)10-3-11-32(26(33)29-21-6-9-25(28)24(27)18-21)22-7-4-19-5-8-23(34-2)17-20(19)16-22/h5-6,8-9,17-18,22H,3-4,7,10-16H2,1-2H3,(H,29,33)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacopeia Drug Discovery Inc. Curated by ChEMBL					Assay Description Inhibition of 125I-MCH binding to human MCH-R1 expressed in CHO cell membranes				Bioorg Med Chem Lett 17: 1718-21 (2007) Article DOI: 10.1016/j.bmcl.2006.12.080 BindingDB Entry DOI: 10.7270/Q26H4H3Q
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