null

SMILES: C[C@H](NS(=O)(=O)C1CC1)[C@H](Oc1ccc2n(ncc2c1)-c1ccc(F)cc1)c1ccccc1

InChI Key: InChIKey=JZASNJOSLMESTC-GKVSMKOHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50203417   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor beta (Homo sapiens (Human))	BDBM50203417 (CHEMBL3914142) Show SMILES C[C@H](NS(=O)(=O)C1CC1)[C@H](Oc1ccc2n(ncc2c1)-c1ccc(F)cc1)c1ccccc1 |r| Show InChI InChI=1S/C25H24FN3O3S/c1-17(28-33(30,31)23-12-13-23)25(18-5-3-2-4-6-18)32-22-11-14-24-19(15-22)16-27-29(24)21-9-7-20(26)8-10-21/h2-11,14-17,23,25,28H,12-13H2,1H3/t17-,25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to ERbeta (unknown origin) by FP assay				Bioorg Med Chem Lett 26: 5741-5748 (2016) Article DOI: 10.1016/j.bmcl.2016.10.052 BindingDB Entry DOI: 10.7270/Q2NP26D1
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50203417 (CHEMBL3914142) Show SMILES C[C@H](NS(=O)(=O)C1CC1)[C@H](Oc1ccc2n(ncc2c1)-c1ccc(F)cc1)c1ccccc1 |r| Show InChI InChI=1S/C25H24FN3O3S/c1-17(28-33(30,31)23-12-13-23)25(18-5-3-2-4-6-18)32-22-11-14-24-19(15-22)16-27-29(24)21-9-7-20(26)8-10-21/h2-11,14-17,23,25,28H,12-13H2,1H3/t17-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to GR (unknown origin) by FP assay				Bioorg Med Chem Lett 26: 5741-5748 (2016) Article DOI: 10.1016/j.bmcl.2016.10.052 BindingDB Entry DOI: 10.7270/Q2NP26D1
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM50203417 (CHEMBL3914142) Show SMILES C[C@H](NS(=O)(=O)C1CC1)[C@H](Oc1ccc2n(ncc2c1)-c1ccc(F)cc1)c1ccccc1 |r| Show InChI InChI=1S/C25H24FN3O3S/c1-17(28-33(30,31)23-12-13-23)25(18-5-3-2-4-6-18)32-22-11-14-24-19(15-22)16-27-29(24)21-9-7-20(26)8-10-21/h2-11,14-17,23,25,28H,12-13H2,1H3/t17-,25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to ERalpha (unknown origin) by FP assay				Bioorg Med Chem Lett 26: 5741-5748 (2016) Article DOI: 10.1016/j.bmcl.2016.10.052 BindingDB Entry DOI: 10.7270/Q2NP26D1
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50203417 (CHEMBL3914142) Show SMILES C[C@H](NS(=O)(=O)C1CC1)[C@H](Oc1ccc2n(ncc2c1)-c1ccc(F)cc1)c1ccccc1 |r| Show InChI InChI=1S/C25H24FN3O3S/c1-17(28-33(30,31)23-12-13-23)25(18-5-3-2-4-6-18)32-22-11-14-24-19(15-22)16-27-29(24)21-9-7-20(26)8-10-21/h2-11,14-17,23,25,28H,12-13H2,1H3/t17-,25-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to AR (unknown origin) by FP assay				Bioorg Med Chem Lett 26: 5741-5748 (2016) Article DOI: 10.1016/j.bmcl.2016.10.052 BindingDB Entry DOI: 10.7270/Q2NP26D1
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50203417 (CHEMBL3914142) Show SMILES C[C@H](NS(=O)(=O)C1CC1)[C@H](Oc1ccc2n(ncc2c1)-c1ccc(F)cc1)c1ccccc1 |r| Show InChI InChI=1S/C25H24FN3O3S/c1-17(28-33(30,31)23-12-13-23)25(18-5-3-2-4-6-18)32-22-11-14-24-19(15-22)16-27-29(24)21-9-7-20(26)8-10-21/h2-11,14-17,23,25,28H,12-13H2,1H3/t17-,25-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of 3H-aldosterone from MR (unknown origin) ligand binding domain by SPA assay				Bioorg Med Chem Lett 26: 5741-5748 (2016) Article DOI: 10.1016/j.bmcl.2016.10.052 BindingDB Entry DOI: 10.7270/Q2NP26D1
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50203417 (CHEMBL3914142) Show SMILES C[C@H](NS(=O)(=O)C1CC1)[C@H](Oc1ccc2n(ncc2c1)-c1ccc(F)cc1)c1ccccc1 |r| Show InChI InChI=1S/C25H24FN3O3S/c1-17(28-33(30,31)23-12-13-23)25(18-5-3-2-4-6-18)32-22-11-14-24-19(15-22)16-27-29(24)21-9-7-20(26)8-10-21/h2-11,14-17,23,25,28H,12-13H2,1H3/t17-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.910	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Agonist activity at glucocorticoid receptor in human ChaGoK1 cells assessed as inhibition of AP1-mediated transcriptional activity by measuring reduc...				Bioorg Med Chem Lett 26: 5741-5748 (2016) Article DOI: 10.1016/j.bmcl.2016.10.052 BindingDB Entry DOI: 10.7270/Q2NP26D1
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50203417 (CHEMBL3914142) Show SMILES C[C@H](NS(=O)(=O)C1CC1)[C@H](Oc1ccc2n(ncc2c1)-c1ccc(F)cc1)c1ccccc1 |r| Show InChI InChI=1S/C25H24FN3O3S/c1-17(28-33(30,31)23-12-13-23)25(18-5-3-2-4-6-18)32-22-11-14-24-19(15-22)16-27-29(24)21-9-7-20(26)8-10-21/h2-11,14-17,23,25,28H,12-13H2,1H3/t17-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Binding affinity to PR (unknown origin) by FP assay				Bioorg Med Chem Lett 26: 5741-5748 (2016) Article DOI: 10.1016/j.bmcl.2016.10.052 BindingDB Entry DOI: 10.7270/Q2NP26D1
					More data for this Ligand-Target Pair