BDBM50203508 CHEMBL3968165

SMILES: OC(=O)c1ccc(cc1)-n1nc(Oc2c(Cl)cccc2Cl)c2ccccc12

InChI Key: InChIKey=GPFWRNYBYBBENI-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50203508   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear receptor ROR-gamma (RORC) (Homo sapiens (Human))	BDBM50203508 (CHEMBL3968165) Show SMILES OC(=O)c1ccc(cc1)-n1nc(Oc2c(Cl)cccc2Cl)c2ccccc12 Show InChI InChI=1S/C20H12Cl2N2O3/c21-15-5-3-6-16(22)18(15)27-19-14-4-1-2-7-17(14)24(23-19)13-10-8-12(9-11-13)20(25)26/h1-11H,(H,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Galderma R&D Curated by ChEMBL					Assay Description Inverse agonist activity at GAL4 DBD-fused RORgammat LBD (unknown origin) expressed in HG5LN cells after 18 hrs by luciferase reporter gene assay				Bioorg Med Chem Lett 26: 5802-5808 (2016) Article DOI: 10.1016/j.bmcl.2016.10.023 BindingDB Entry DOI: 10.7270/Q2D79DDH
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50203508 (CHEMBL3968165) Show SMILES OC(=O)c1ccc(cc1)-n1nc(Oc2c(Cl)cccc2Cl)c2ccccc12 Show InChI InChI=1S/C20H12Cl2N2O3/c21-15-5-3-6-16(22)18(15)27-19-14-4-1-2-7-17(14)24(23-19)13-10-8-12(9-11-13)20(25)26/h1-11H,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Galderma R&D Curated by ChEMBL					Assay Description Inverse agonist activity at GAL4 DBD-fused RARgamma LBD (unknown origin) expressed in human HG5LN cells after 18 hrs by luciferase reporter gene assa...				Bioorg Med Chem Lett 26: 5802-5808 (2016) Article DOI: 10.1016/j.bmcl.2016.10.023 BindingDB Entry DOI: 10.7270/Q2D79DDH
					More data for this Ligand-Target Pair