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SMILES: Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)OCCCN1CCCC1

InChI Key: InChIKey=BRFSLLFZOHATFX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50203869   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
C-C chemokine receptor type 8


(Homo sapiens (Human))		BDBM50203869
PNG
(3-pyrrolidin-1-ylpropyl 4-[({4-[(2-methylbenzoyl)a...)
Show SMILES Cc1ccccc1C(=O)Nc1ccc(c2ccccc12)S(=O)(=O)NC1CCN(CC1)C(=O)OCCCN1CCCC1
Show InChI InChI=1S/C31H38N4O5S/c1-23-9-2-3-10-25(23)30(36)32-28-13-14-29(27-12-5-4-11-26(27)28)41(38,39)33-24-15-20-35(21-16-24)31(37)40-22-8-19-34-17-6-7-18-34/h2-5,9-14,24,33H,6-8,15-22H2,1H3,(H,32,36)
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Similars
Article
PubMed
n/an/a 4.20n/an/an/an/an/an/a



Millennium Pharmaceuticals

Curated by ChEMBL


Assay Description
Antagonist activity against human CCR8 expressed in CHO/Galpha16 cells assessed as inhibition of CCL1-induced increase of intracellular calcium by FL...

J Med Chem 50: 566-84 (2007)


Article DOI: 10.1021/jm061118e
BindingDB Entry DOI: 10.7270/Q24J0DSN
More data for this
Ligand-Target Pair