BDBM50204445 CHEMBL234960::N-(3,3-dimethylbutan-2-yl)-N-methyl-1-oxo-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-6-carboxamide

SMILES: CC(N(C)C(=O)c1ccc2[nH]c3c(CCNC3=O)c2c1)C(C)(C)C

InChI Key: InChIKey=GGKLTQPANCHLHR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50204445   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (RAT)	BDBM50204445 (CHEMBL234960 | N-(3,3-dimethylbutan-2-yl)-N-methyl...) Show SMILES CC(N(C)C(=O)c1ccc2[nH]c3c(CCNC3=O)c2c1)C(C)(C)C |w:1.0| Show InChI InChI=1S/C19H25N3O2/c1-11(19(2,3)4)22(5)18(24)12-6-7-15-14(10-12)13-8-9-20-17(23)16(13)21-15/h6-7,10-11,21H,8-9H2,1-5H3,(H,20,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description Antagonist activity at rat mGluR1a expressed in CHO cells assessed as inhibition of intracellular calcium ion mobilization by FLIPR assay				Bioorg Med Chem Lett 17: 2254-9 (2007) Article DOI: 10.1016/j.bmcl.2007.01.055 BindingDB Entry DOI: 10.7270/Q2FT8KPZ
					More data for this Ligand-Target Pair