BDBM50204504 6-(2-(7-phenylheptanoyl)oxazol-5-yl)nicotinic acid::CHEMBL219953

SMILES: OC(=O)c1ccc(nc1)-c1cnc(o1)C(=O)CCCCCCc1ccccc1

InChI Key: InChIKey=SHWZOKMNLUJQPA-UHFFFAOYSA-N

Data: 3 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50204504   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50204504 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)nicotinic acid...) Show SMILES OC(=O)c1ccc(nc1)-c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C22H22N2O4/c25-19(11-7-2-1-4-8-16-9-5-3-6-10-16)21-24-15-20(28-21)18-13-12-17(14-23-18)22(26)27/h3,5-6,9-10,12-15H,1-2,4,7-8,11H2,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdown				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50204504 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)nicotinic acid...) Show SMILES OC(=O)c1ccc(nc1)-c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C22H22N2O4/c25-19(11-7-2-1-4-8-16-9-5-3-6-10-16)21-24-15-20(28-21)18-13-12-17(14-23-18)22(26)27/h3,5-6,9-10,12-15H,1-2,4,7-8,11H2,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human FAAH expressed in COS7 cells by [14C]oleamide breakdown				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat))	BDBM50204504 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)nicotinic acid...) Show SMILES OC(=O)c1ccc(nc1)-c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C22H22N2O4/c25-19(11-7-2-1-4-8-16-9-5-3-6-10-16)21-24-15-20(28-21)18-13-12-17(14-23-18)22(26)27/h3,5-6,9-10,12-15H,1-2,4,7-8,11H2,(H,26,27)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of recombinant rat FAAH expressed in Escherichia coli assessed as breakdown of [14C]-oleamide by Dixon plot analysis				J Med Chem 57: 1079-89 (2014) Article DOI: 10.1021/jm401820q BindingDB Entry DOI: 10.7270/Q2HX1F5K
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50204504 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)nicotinic acid...) Show SMILES OC(=O)c1ccc(nc1)-c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C22H22N2O4/c25-19(11-7-2-1-4-8-16-9-5-3-6-10-16)21-24-15-20(28-21)18-13-12-17(14-23-18)22(26)27/h3,5-6,9-10,12-15H,1-2,4,7-8,11H2,(H,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of rat recombinant FAAH expressed in Escherichia coli by [14C]oleamide breakdown				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
					More data for this Ligand-Target Pair
Acyl-CoA: cholesterol acyltransferase (ACAT) (Homo sapiens (Human))	BDBM50204504 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)nicotinic acid...) Show SMILES OC(=O)c1ccc(nc1)-c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C22H22N2O4/c25-19(11-7-2-1-4-8-16-9-5-3-6-10-16)21-24-15-20(28-21)18-13-12-17(14-23-18)22(26)27/h3,5-6,9-10,12-15H,1-2,4,7-8,11H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of TGH				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
					More data for this Ligand-Target Pair
Neutral cholesterol ester hydrolase 1 (Homo sapiens (Human))	BDBM50204504 (6-(2-(7-phenylheptanoyl)oxazol-5-yl)nicotinic acid...) Show SMILES OC(=O)c1ccc(nc1)-c1cnc(o1)C(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C22H22N2O4/c25-19(11-7-2-1-4-8-16-9-5-3-6-10-16)21-24-15-20(28-21)18-13-12-17(14-23-18)22(26)27/h3,5-6,9-10,12-15H,1-2,4,7-8,11H2,(H,26,27)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of KIAA1363				J Med Chem 50: 1058-68 (2007) Article DOI: 10.1021/jm0611509 BindingDB Entry DOI: 10.7270/Q26H4J6G
					More data for this Ligand-Target Pair