BDBM50204535 CHEMBL3972536

SMILES: Clc1cc(Cl)c(OCCOc2cccnc2)c(C=O)c1

InChI Key: InChIKey=ZTZSZAVWXYECHR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204535   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium release-activated calcium channel (Homo sapiens (Human))	BDBM50204535 (CHEMBL3972536) Show SMILES Clc1cc(Cl)c(OCCOc2cccnc2)c(C=O)c1 Show InChI InChI=1S/C14H11Cl2NO3/c15-11-6-10(9-18)14(13(16)7-11)20-5-4-19-12-2-1-3-17-8-12/h1-3,6-9H,4-5H2	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction in BAPTA-induced Ca2+ depletion-stimulated SOC...				Bioorg Med Chem 25: 440-449 (2017) Article DOI: 10.1016/j.bmc.2016.11.007 BindingDB Entry DOI: 10.7270/Q2HT2R9F
					More data for this Ligand-Target Pair
Calcium release-activated calcium channel (Homo sapiens (Human))	BDBM50204535 (CHEMBL3972536) Show SMILES Clc1cc(Cl)c(OCCOc2cccnc2)c(C=O)c1 Show InChI InChI=1S/C14H11Cl2NO3/c15-11-6-10(9-18)14(13(16)7-11)20-5-4-19-12-2-1-3-17-8-12/h1-3,6-9H,4-5H2	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Inhibition of Orai1-mediated store operated Ca2+ entry in human MDA-MB-231 cells assessed as reduction of SERCA inhibition-induced ER release preincu...				Bioorg Med Chem 25: 440-449 (2017) Article DOI: 10.1016/j.bmc.2016.11.007 BindingDB Entry DOI: 10.7270/Q2HT2R9F
					More data for this Ligand-Target Pair