BDBM50204578 CHEMBL399008::N-tert-butyl-5-phenyl-6-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)furo[2,3-d]pyrimidin-4-amine

SMILES: CC(C)(C)Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccc(OCCN2CCCC2)cc1

InChI Key: InChIKey=GZBRMTRCRSMBNA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50204578   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50204578 (CHEMBL399008 | N-tert-butyl-5-phenyl-6-(4-(2-(pyrr...) Show SMILES CC(C)(C)Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccc(OCCN2CCCC2)cc1 Show InChI InChI=1S/C28H32N4O2/c1-28(2,3)31-26-24-23(20-9-5-4-6-10-20)25(34-27(24)30-19-29-26)21-11-13-22(14-12-21)33-18-17-32-15-7-8-16-32/h4-6,9-14,19H,7-8,15-18H2,1-3H3,(H,29,30,31)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Lck				Bioorg Med Chem Lett 17: 2305-9 (2007) Article DOI: 10.1016/j.bmcl.2007.01.057 BindingDB Entry DOI: 10.7270/Q2697365
					More data for this Ligand-Target Pair
Tyrosine kinase non-receptor protein 2 (Homo sapiens (Human))	BDBM50204578 (CHEMBL399008 | N-tert-butyl-5-phenyl-6-(4-(2-(pyrr...) Show SMILES CC(C)(C)Nc1ncnc2oc(c(-c3ccccc3)c12)-c1ccc(OCCN2CCCC2)cc1 Show InChI InChI=1S/C28H32N4O2/c1-28(2,3)31-26-24-23(20-9-5-4-6-10-20)25(34-27(24)30-19-29-26)21-11-13-22(14-12-21)33-18-17-32-15-7-8-16-32/h4-6,9-14,19H,7-8,15-18H2,1-3H3,(H,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Ack1				Bioorg Med Chem Lett 17: 2305-9 (2007) Article DOI: 10.1016/j.bmcl.2007.01.057 BindingDB Entry DOI: 10.7270/Q2697365
					More data for this Ligand-Target Pair