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SMILES: CNCc1ccc(C)c(c1)-c1ccccc1OC

InChI Key: InChIKey=YVGUQAHJAMDDHE-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50204667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204667 (CHEMBL3943658) Show SMILES CNCc1ccc(C)c(c1)-c1ccccc1OC Show InChI InChI=1S/C16H19NO/c1-12-8-9-13(11-17-2)10-15(12)14-6-4-5-7-16(14)18-3/h4-10,17H,11H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Displacement of [3H]D-lysergic acid diethylamide from 5HT7R (unknown origin) expressed in HEK293 cell membranes incubated for 1.5 hrs in absence of l...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204667 (CHEMBL3943658) Show SMILES CNCc1ccc(C)c(c1)-c1ccccc1OC Show InChI InChI=1S/C16H19NO/c1-12-8-9-13(11-17-2)10-15(12)14-6-4-5-7-16(14)18-3/h4-10,17H,11H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Agonist activity at human 5-HT7R expressed in HEK293 cells assessed as induction of cAMP levels treated for 10 mins measured after 30 mins by D2-dye ...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50204667 (CHEMBL3943658) Show SMILES CNCc1ccc(C)c(c1)-c1ccccc1OC Show InChI InChI=1S/C16H19NO/c1-12-8-9-13(11-17-2)10-15(12)14-6-4-5-7-16(14)18-3/h4-10,17H,11H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a
Yonsei University Curated by ChEMBL					Assay Description Agonist activity at human 5-HT7R expressed in HEK293 cells assessed as induction of cAMP levels treated for 10 mins measured after 30 mins by D2-dye ...				Eur J Med Chem 123: 180-190 (2016) Article DOI: 10.1016/j.ejmech.2016.07.029 BindingDB Entry DOI: 10.7270/Q27D2X36
					More data for this Ligand-Target Pair