BDBM50205136 (2S)-1-{[(2S,4R)-4-(3-hydroxy-2,6-dimethylphenyl)-2-pyrrolidinyl]carbonyl}-2-pyrrolidinecarbonitrile::(S)-1-((2S,4R)-4-(3-hydroxy-2,6-dimethylphenyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carbonitrile::CHEMBL413797

SMILES: Cc1ccc(O)c(C)c1[C@@H]1CN[C@@H](C1)C(=O)N1CCC[C@H]1C#N

InChI Key: InChIKey=RMRDUAVIGASCCM-KKUMJFAQSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50205136   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50205136 ((2S)-1-{[(2S,4R)-4-(3-hydroxy-2,6-dimethylphenyl)-...) Show SMILES Cc1ccc(O)c(C)c1[C@@H]1CN[C@@H](C1)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C18H23N3O2/c1-11-5-6-16(22)12(2)17(11)13-8-15(20-10-13)18(23)21-7-3-4-14(21)9-19/h5-6,13-15,20,22H,3-4,7-8,10H2,1-2H3/t13-,14-,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Matrix Laboratories Limited Curated by ChEMBL					Assay Description Inhibition of human DPP4				Bioorg Med Chem 17: 1783-802 (2009) Article DOI: 10.1016/j.bmc.2009.01.061 BindingDB Entry DOI: 10.7270/Q2VD70DJ
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50205136 ((2S)-1-{[(2S,4R)-4-(3-hydroxy-2,6-dimethylphenyl)-...) Show SMILES Cc1ccc(O)c(C)c1[C@@H]1CN[C@@H](C1)C(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C18H23N3O2/c1-11-5-6-16(22)12(2)17(11)13-8-15(20-10-13)18(23)21-7-3-4-14(21)9-19/h5-6,13-15,20,22H,3-4,7-8,10H2,1-2H3/t13-,14-,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Minase Research Institute Curated by ChEMBL					Assay Description Inhibition of human DPP4				Bioorg Med Chem 15: 2715-35 (2007) Article DOI: 10.1016/j.bmc.2007.01.033 BindingDB Entry DOI: 10.7270/Q2NC60W7
					More data for this Ligand-Target Pair