BDBM50205347 CHEMBL3947950

SMILES: CC1(C)C[C@@H](N(C1)c1ccn2ncc(NC(=O)c3cnccn3)c2n1)c1cc(F)ccc1F

InChI Key: InChIKey=DTAWNRUMOCQMSC-LJQANCHMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205347   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50205347 (CHEMBL3947950) Show SMILES CC1(C)C[C@@H](N(C1)c1ccn2ncc(NC(=O)c3cnccn3)c2n1)c1cc(F)ccc1F |r| Show InChI InChI=1S/C23H21F2N7O/c1-23(2)10-19(15-9-14(24)3-4-16(15)25)31(13-23)20-5-8-32-21(30-20)17(12-28-32)29-22(33)18-11-26-6-7-27-18/h3-9,11-12,19H,10,13H2,1-2H3,(H,29,33)/t19-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Dongguk University Curated by ChEMBL					Assay Description Inhibition of TrkA (unknown origin) by ELISA				Bioorg Med Chem 25: 389-396 (2017) Article DOI: 10.1016/j.bmc.2016.11.005 BindingDB Entry DOI: 10.7270/Q2JM2CNM
					More data for this Ligand-Target Pair