BDBM50205471 CHEMBL3927718

SMILES: Cc1cccc(c1)-c1c(nnn1CC(=O)Nc1ccc(cn1)-c1ccccc1)-c1ccncc1

InChI Key: InChIKey=LUSRFCREHQMMJI-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205471   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable protein-cysteine N-palmitoyltransferase porcupine (Mus musculus)	BDBM50205471 (CHEMBL3927718) Show SMILES Cc1cccc(c1)-c1c(nnn1CC(=O)Nc1ccc(cn1)-c1ccccc1)-c1ccncc1 Show InChI InChI=1S/C27H22N6O/c1-19-6-5-9-22(16-19)27-26(21-12-14-28-15-13-21)31-32-33(27)18-25(34)30-24-11-10-23(17-29-24)20-7-3-2-4-8-20/h2-17H,18H2,1H3,(H,29,30,34)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
UT Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of porcupine-mediated Wnt signaling in mouse L-cells after 24 hrs by springerImage-Topflash reporter assay				Bioorg Med Chem Lett 26: 5891-5895 (2016) Article DOI: 10.1016/j.bmcl.2016.11.012 BindingDB Entry DOI: 10.7270/Q2959KJR
					More data for this Ligand-Target Pair