BDBM50205514 4-{2-[5-chloro-2-(2-{[(4-chlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]ethoxy}benzoic acid::CHEMBL375997

SMILES: OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccc(Cl)cc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1

InChI Key: InChIKey=ZHHDCBLVPXBKBS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205514   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cPLA2 C2 (Homo sapiens (Human))	BDBM50205514 (4-{2-[5-chloro-2-(2-{[(4-chlorobenzyl)sulfonyl]ami...) Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccc(Cl)cc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C39H34Cl2N2O5S/c40-31-15-11-27(12-16-31)26-49(46,47)42-23-21-37-34(22-24-48-33-18-13-30(14-19-33)39(44)45)35-25-32(41)17-20-36(35)43(37)38(28-7-3-1-4-8-28)29-9-5-2-6-10-29/h1-20,25,38,42H,21-24,26H2,(H,44,45)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human cPLA2 alpha by GLU micelle assay				J Med Chem 50: 1380-400 (2007) Article DOI: 10.1021/jm061131z BindingDB Entry DOI: 10.7270/Q23F4PB9
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