BDBM50205537 4-(2-(1-benzhydryl-5-chloro-2-(2-(phenylmethylsulfonamido)ethyl)-1H-indol-3-yl)ethoxy)benzoic acid::4-[2-(1-benzhydryl-2-{2-[(benzylsulfonyl)amino]ethyl}-5-chloro-1H-indol-3 -yl)ethoxy]benzoic acid::CHEMBL373778

SMILES: OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1

InChI Key: InChIKey=MRFCFORIRNDBEX-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50205537   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cPLA2 C2 (Homo sapiens (Human))	BDBM50205537 (4-(2-(1-benzhydryl-5-chloro-2-(2-(phenylmethylsulf...) Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C39H35ClN2O5S/c40-32-18-21-36-35(26-32)34(23-25-47-33-19-16-31(17-20-33)39(43)44)37(22-24-41-48(45,46)27-28-10-4-1-5-11-28)42(36)38(29-12-6-2-7-13-29)30-14-8-3-9-15-30/h1-21,26,38,41H,22-25,27H2,(H,43,44)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human cytosolic PLA2alpha by GLU micelle assay				J Med Chem 52: 1156-71 (2009) Article DOI: 10.1021/jm8009876 BindingDB Entry DOI: 10.7270/Q20C4VSK
					More data for this Ligand-Target Pair
cPLA2 C2 (Homo sapiens (Human))	BDBM50205537 (4-(2-(1-benzhydryl-5-chloro-2-(2-(phenylmethylsulf...) Show SMILES OC(=O)c1ccc(OCCc2c(CCNS(=O)(=O)Cc3ccccc3)n(C(c3ccccc3)c3ccccc3)c3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C39H35ClN2O5S/c40-32-18-21-36-35(26-32)34(23-25-47-33-19-16-31(17-20-33)39(43)44)37(22-24-41-48(45,46)27-28-10-4-1-5-11-28)42(36)38(29-12-6-2-7-13-29)30-14-8-3-9-15-30/h1-21,26,38,41H,22-25,27H2,(H,43,44)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of human cPLA2 alpha by GLU micelle assay				J Med Chem 50: 1380-400 (2007) Article DOI: 10.1021/jm061131z BindingDB Entry DOI: 10.7270/Q23F4PB9
					More data for this Ligand-Target Pair