BDBM50205552 5-(6,7-bis(2-methoxyethoxy)quinazolin-4-ylamino)-2-chloro-4-fluorophenol::CHEMBL396219

SMILES: COCCOc1cc2ncnc(Nc3cc(O)c(Cl)cc3F)c2cc1OCCOC

InChI Key: InChIKey=OAQPUVWKEKSUAZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205552   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50205552 (5-(6,7-bis(2-methoxyethoxy)quinazolin-4-ylamino)-2...) Show SMILES COCCOc1cc2ncnc(Nc3cc(O)c(Cl)cc3F)c2cc1OCCOC Show InChI InChI=1S/C20H21ClFN3O5/c1-27-3-5-29-18-7-12-15(10-19(18)30-6-4-28-2)23-11-24-20(12)25-16-9-17(26)13(21)8-14(16)22/h7-11,26H,3-6H2,1-2H3,(H,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Jiaotong University Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 2126-33 (2007) Article DOI: 10.1016/j.bmcl.2007.01.089 BindingDB Entry DOI: 10.7270/Q2S1839D
					More data for this Ligand-Target Pair