BDBM50205554 2-chloro-4-fluoro-5-(7-(2-methoxyethoxy)quinazolin-4-ylamino)phenol::CHEMBL231650

SMILES: COCCOc1ccc2c(Nc3cc(O)c(Cl)cc3F)ncnc2c1

InChI Key: InChIKey=BIKCGYWZXMEPEQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205554   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50205554 (2-chloro-4-fluoro-5-(7-(2-methoxyethoxy)quinazolin...) Show SMILES COCCOc1ccc2c(Nc3cc(O)c(Cl)cc3F)ncnc2c1 Show InChI InChI=1S/C17H15ClFN3O3/c1-24-4-5-25-10-2-3-11-14(6-10)20-9-21-17(11)22-15-8-16(23)12(18)7-13(15)19/h2-3,6-9,23H,4-5H2,1H3,(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Jiaotong University Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 2126-33 (2007) Article DOI: 10.1016/j.bmcl.2007.01.089 BindingDB Entry DOI: 10.7270/Q2S1839D
					More data for this Ligand-Target Pair