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BDBM50205607 CHEMBL3925358

SMILES: COc1ccc(cc1OC)C1=NN(CC(N)=O)C(=O)CCC1

InChI Key:

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205607   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))
BDBM50205607
PNG
(CHEMBL3925358)
Show SMILES COc1ccc(cc1OC)C1=NN(CC(N)=O)C(=O)CCC1 |t:11|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.55E+3n/an/an/an/an/an/a



University of Genoa

Curated by ChEMBL


Assay Description
Inhibition of human recombinant PDE4B2 using cAMP as substrate after 2 hrs by TR-FRET assay


Bioorg Med Chem Lett 27: 24-29 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.040
BindingDB Entry DOI: 10.7270/Q21N8333
More data for this
Ligand-Target Pair