BDBM50205642 CHEMBL3742387

SMILES: FC(F)(F)c1ccc(cc1)C(=O)c1nccc2c3ccccc3[nH]c12

InChI Key: InChIKey=FHKLTXMZKQMWDB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50205642   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholinesterases (Homo sapiens (Human))	BDBM50205642 (CHEMBL3742387) Show SMILES FC(F)(F)c1ccc(cc1)C(=O)c1nccc2c3ccccc3[nH]c12 Show InChI InChI=1S/C19H11F3N2O/c20-19(21,22)12-7-5-11(6-8-12)18(25)17-16-14(9-10-23-17)13-3-1-2-4-15(13)24-16/h1-10,24H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Massachusetts Boston Curated by ChEMBL					Assay Description Inhibition of BuChE (unknown origin) by spectrophotometric analysis based Ellman's assay				Bioorg Med Chem Lett 27: 232-236 (2017) Article DOI: 10.1016/j.bmcl.2016.11.067 BindingDB Entry DOI: 10.7270/Q2NC636H
					More data for this Ligand-Target Pair