BDBM50205797 5-(4-fluorophenethyl)-2-(4-fluorophenylsulfonyl)pyridine::CHEMBL240246

SMILES: Fc1ccc(CCc2ccc(nc2)S(=O)(=O)c2ccc(F)cc2)cc1

InChI Key: InChIKey=PABZJFZRAJANGX-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50205797   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50205797 (5-(4-fluorophenethyl)-2-(4-fluorophenylsulfonyl)py...) Show SMILES Fc1ccc(CCc2ccc(nc2)S(=O)(=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C19H15F2NO2S/c20-16-6-3-14(4-7-16)1-2-15-5-12-19(22-13-15)25(23,24)18-10-8-17(21)9-11-18/h3-13H,1-2H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5HT2A receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 2643-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.098 BindingDB Entry DOI: 10.7270/Q2F47PZH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50205797 (5-(4-fluorophenethyl)-2-(4-fluorophenylsulfonyl)py...) Show SMILES Fc1ccc(CCc2ccc(nc2)S(=O)(=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C19H15F2NO2S/c20-16-6-3-14(4-7-16)1-2-15-5-12-19(22-13-15)25(23,24)18-10-8-17(21)9-11-18/h3-13H,1-2H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2 receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 2643-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.098 BindingDB Entry DOI: 10.7270/Q2F47PZH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50205797 (5-(4-fluorophenethyl)-2-(4-fluorophenylsulfonyl)py...) Show SMILES Fc1ccc(CCc2ccc(nc2)S(=O)(=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C19H15F2NO2S/c20-16-6-3-14(4-7-16)1-2-15-5-12-19(22-13-15)25(23,24)18-10-8-17(21)9-11-18/h3-13H,1-2H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Curated by ChEMBL					Assay Description Displacement of [3H]mesurgeline from human 5HT2C receptor expressed in CHO cells				Bioorg Med Chem Lett 17: 2643-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.098 BindingDB Entry DOI: 10.7270/Q2F47PZH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50205797 (5-(4-fluorophenethyl)-2-(4-fluorophenylsulfonyl)py...) Show SMILES Fc1ccc(CCc2ccc(nc2)S(=O)(=O)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C19H15F2NO2S/c20-16-6-3-14(4-7-16)1-2-15-5-12-19(22-13-15)25(23,24)18-10-8-17(21)9-11-18/h3-13H,1-2H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from hERG expressed in HEK cells				Bioorg Med Chem Lett 17: 2643-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.098 BindingDB Entry DOI: 10.7270/Q2F47PZH
					More data for this Ligand-Target Pair