BDBM50206090 CHEMBL3915405
SMILES: OC(=O)C(F)(F)F.NCCOCCOc1ccc2nc(ccc2c1)-c1cn(nn1)-c1ccc(O)cc1
InChI Key: InChIKey=RXYWXMDDVUSFNI-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Macrophage migration inhibitory factor (MIF) (Homo sapiens (Human)) | BDBM50206090 (CHEMBL3915405) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as borate-enol complex formation using 4-hydroxypheny... | ACS Med Chem Lett 8: 124-127 (2017) Article DOI: 10.1021/acsmedchemlett.6b00451 BindingDB Entry DOI: 10.7270/Q2GQ70S5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (MIF) (Homo sapiens (Human)) | BDBM50206090 (CHEMBL3915405) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity expressed in Escherichia coli assessed as decrease in formation of borate complex of enol pr... | ACS Med Chem Lett 8: 1287-1291 (2017) Article DOI: 10.1021/acsmedchemlett.7b00384 BindingDB Entry DOI: 10.7270/Q2GB26JT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Macrophage migration inhibitory factor (MIF) (Homo sapiens (Human)) | BDBM50206090 (CHEMBL3915405) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a |
Yale University Curated by ChEMBL | Assay Description Inhibition of recombinant human MIF tautomerase activity assessed as decrease in formation of borate complex of enol product using 4-HPP as substrate... | ACS Med Chem Lett 8: 1287-1291 (2017) Article DOI: 10.1021/acsmedchemlett.7b00384 BindingDB Entry DOI: 10.7270/Q2GB26JT | |||||||||||
More data for this Ligand-Target Pair |