BDBM50206273 5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1H-indol-4-yl)pyrimidin-2-amine::CHEMBL392743

SMILES: CN(C)CCc1ccc(Nc2ncc(Cl)c(n2)-c2cccc3[nH]ccc23)cc1

InChI Key: InChIKey=MYCZGGLQZWGNBJ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206273   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50206273 (5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...) Show SMILES CN(C)CCc1ccc(Nc2ncc(Cl)c(n2)-c2cccc3[nH]ccc23)cc1 Show InChI InChI=1S/C22H22ClN5/c1-28(2)13-11-15-6-8-16(9-7-15)26-22-25-14-19(23)21(27-22)18-4-3-5-20-17(18)10-12-24-20/h3-10,12,14,24H,11,13H2,1-2H3,(H,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibition of CDK1				Bioorg Med Chem Lett 17: 2179-83 (2007) Article DOI: 10.1016/j.bmcl.2007.01.086 BindingDB Entry DOI: 10.7270/Q2CR5T2B
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50206273 (5-chloro-N-(4-(2-(dimethylamino)ethyl)phenyl)-4-(1...) Show SMILES CN(C)CCc1ccc(Nc2ncc(Cl)c(n2)-c2cccc3[nH]ccc23)cc1 Show InChI InChI=1S/C22H22ClN5/c1-28(2)13-11-15-6-8-16(9-7-15)26-22-25-14-19(23)21(27-22)18-4-3-5-20-17(18)10-12-24-20/h3-10,12,14,24H,11,13H2,1-2H3,(H,25,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	216	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibiton of VEGFR2				Bioorg Med Chem Lett 17: 2179-83 (2007) Article DOI: 10.1016/j.bmcl.2007.01.086 BindingDB Entry DOI: 10.7270/Q2CR5T2B
					More data for this Ligand-Target Pair