BDBM50206320 CHEMBL3962223

SMILES: CCCCNC(=O)c1c(N)sc(c1CCCC)-c1ccccc1

InChI Key: InChIKey=AVOUQSFLCQIECA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50206320   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 15-lipoxygenase (Homo sapiens (Human))	BDBM50206320 (CHEMBL3962223) Show SMILES CCCCNC(=O)c1c(N)sc(c1CCCC)-c1ccccc1 Show InChI InChI=1S/C19H26N2OS/c1-3-5-12-15-16(19(22)21-13-6-4-2)18(20)23-17(15)14-10-8-7-9-11-14/h7-11H,3-6,12-13,20H2,1-2H3,(H,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Groningen Curated by ChEMBL					Assay Description Inhibition of human 15-LOX-1 assessed as reduction in conversion of linoleic acid to 13(S)-HpODE incubated for 10 mins followed by linoleic acid addi...				Eur J Med Chem 122: 786-801 (2016) Article DOI: 10.1016/j.ejmech.2016.07.010 BindingDB Entry DOI: 10.7270/Q2V126S8
					More data for this Ligand-Target Pair