BDBM50206399 CHEMBL247700::N-((S)-2-amino-1-(4-hydroxyphenyl)-2-oxoethyl)-6-(1-(4-tert-butylphenyl)-3-(pyridin-2-yl)-1H-pyrazol-5-ylamino)hexanamide
SMILES: CC(C)(C)c1ccc(cc1)-n1nc(cc1NCCCCCC(=O)N[C@H](C(N)=O)c1ccc(O)cc1)-c1ccccn1
InChI Key: InChIKey=KOCFRHIRGKMAQY-PMERELPUSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human)) | BDBM50206399 (CHEMBL247700 | N-((S)-2-amino-1-(4-hydroxyphenyl)-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 170 | n/a | n/a | n/a | n/a |
Merck Serono Geneva Research Center Curated by ChEMBL | Assay Description Agonist activity at human LH receptor expressed in CHO cells assessed as production of cAMP after 60 mins by SPA | Bioorg Med Chem Lett 17: 2080-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.062 BindingDB Entry DOI: 10.7270/Q2VQ32B2 | |||||||||||
More data for this Ligand-Target Pair |