BDBM50206401 CHEMBL246321::N-((S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)-5-(1-(4-tert-butylphenyl)-3-(pyridin-3-yl)-1H-pyrazol-5-yl)pentanamide
SMILES: CC(C)(C)c1ccc(cc1)-n1nc(cc1CCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)-c1cccnc1
InChI Key: InChIKey=CMMQJXFGOBKVCU-LJAQVGFWSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human)) | BDBM50206401 (CHEMBL246321 | N-((S)-1-amino-3-(4-hydroxyphenyl)-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 311 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Serono Geneva Research Center Curated by ChEMBL | Assay Description Displacement of [125I]-hCG from LH receptor | Bioorg Med Chem Lett 17: 2080-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.062 BindingDB Entry DOI: 10.7270/Q2VQ32B2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lutropin-choriogonadotropic hormone receptor (Homo sapiens (Human)) | BDBM50206401 (CHEMBL246321 | N-((S)-1-amino-3-(4-hydroxyphenyl)-...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Merck Serono Geneva Research Center Curated by ChEMBL | Assay Description Agonist activity at human LH receptor expressed in CHO cells assessed as production of cAMP after 60 mins by SPA | Bioorg Med Chem Lett 17: 2080-5 (2007) Article DOI: 10.1016/j.bmcl.2006.12.062 BindingDB Entry DOI: 10.7270/Q2VQ32B2 | |||||||||||
More data for this Ligand-Target Pair |