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BDBM50206404 (S)-N-(1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl)-4-(1-(4-tert-butylphenyl)-3-(pyridin-4-yl)-1H-pyrazol-5-ylamino)butanamide::CHEMBL247504

SMILES: CC(C)(C)c1ccc(cc1)-n1nc(cc1NCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)-c1ccncc1

InChI Key: InChIKey=OKNJBMTYKPDTNW-MHZLTWQESA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50206404   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lutropin-choriogonadotropic hormone receptor


(Homo sapiens (Human))		BDBM50206404
PNG
((S)-N-(1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-y...)
Show SMILES CC(C)(C)c1ccc(cc1)-n1nc(cc1NCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)-c1ccncc1
Show InChI InChI=1S/C31H36N6O3/c1-31(2,3)23-8-10-24(11-9-23)37-28(20-26(36-37)22-14-17-33-18-15-22)34-16-4-5-29(39)35-27(30(32)40)19-21-6-12-25(38)13-7-21/h6-15,17-18,20,27,34,38H,4-5,16,19H2,1-3H3,(H2,32,40)(H,35,39)/t27-/m0/s1
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Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a



Merck Serono Geneva Research Center

Curated by ChEMBL


Assay Description
Agonist activity at human LH receptor expressed in CHO cells assessed as production of cAMP after 60 mins by SPA

Bioorg Med Chem Lett 17: 2080-5 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.062
BindingDB Entry DOI: 10.7270/Q2VQ32B2
More data for this
Ligand-Target Pair